Mostrando entradas con la etiqueta Media Lab. Mostrar todas las entradas
Mostrando entradas con la etiqueta Media Lab. Mostrar todas las entradas

viernes, 25 de diciembre de 2015

This Device Lets You Brew Your Own Drugs At Home

 www.fastcoexist.com
IN BRIEF
New concept technology sees a future that lets people brew their own drugs in their own home--posing numerous positive benefits and (of course) a few possible downsides.

PROTOTYPE
A machine prototype called Farma can let you manufacture your daily prescription of drugs right in your own home. Designed by MIT Media Lab graduate Will Patrick, the concept tech features a green cylinder and uses blue-green algae that’s genetically engineered to produce pharmaceutical drugs.

After the drugs are produced, the device then measures, filters, and dries it into a powder. Once in powder form, it can then be molded into pill form.
Image credit: Farma
Part of my goal of the project is to demonstrate how easy it is to build an at-home system that could ferment microbes,” says Patrick, who designed the Farma gadget during a residency at Autodesk.

Currently, opiates can already be can be brewed in a lab and Artemisinin is made using genetically engineered yeast, which makes the possibility of using synthetic biology as a way to create other drugs feasible.

While still at the very early concept stage, the artist responsible for envisioning the machine believes the technology might be feasible for widespread use in five to ten years.

IMPLICATIONS
The technical challenges lie in genetic engineering and biochemistry —engineering the organisms that can produce the drugs at useful quantities and processing and separating the drugs from the organism,” says Patrick in the release. And soon, the cost might make the tech feasible. As Patrick asserts, “The cost, tools, and knowledge required for genetically modifying organisms are all becoming more accessible. The hardware required for fermentation is fairly rudimentary in comparison.

It’s hard to guarantee that a pill brewed in your own home might meet the same quality and production standards followed by a factory; but there are also implications that large pharmaceutical organizations might want to protect their intellectual property, which means that the biggest obstacles might not be making the technology work; rather, policy and business challenges are far bigger hurdles.

While the artist believes in the potential of the technology and its benefits, he expresses apprehension regarding the possibility of the machine enabling drug addiction.

However, the concept behind it is really meant to make people realize how well synthetic biology can be incorporated into lifestyles and how it could be used to assist individuals. “My main goal with Farma is to provoke the audience to consider how this new technology should be used,” he says.


ORIGINAL: Futurism

domingo, 30 de noviembre de 2014

MIT Media Lab’s Kevin Hu wants to turn the invisible visible


MIT Media Lab’s Kevin Hu wants to turn the invisible visible
Big Data, HCI, Media Lab, MIT, Visualization, 


Photo by Alan Savenor 

Last March, MIT Media Lab Grad student Kevin Hu and his colleague Amy Yu saw their Pantheon project land on the front cover of The New York Times Magazine. Not bad for two grad students who are part of a generation using today’s seemingly unlimited technological innovations to change the world.

Focused on human data interfaces, Hu and his colleagues at the MIT Media Lab are part of the Macro Connections Group led by Cesar A. Hildago, where their sole mantra is “transform data into knowledge.” One of his current projects, DIVE, automatically generates Web-based, interactive visualizations of structured data sets.

What I discovered when I sat down with Kevin is that all those maps we now explore as click-bait on BuzzFeed, The Atlantic, and The Week explaining everything from the conflict in the Middle East to which states are more adulterous, are only going to become more ubiquitous if Kevin gets his way.

DIVE is a way to turn the invisible, visible. We want to democratize data visualization so that anyone with data can map an image that explains things,” said Hu. His goal is to remove the middlemen who interpret data for us.

But he and his classmates also want to know more about human emotions with another project called Quantify. They want a computer that, or should we say “who,” can feel out the squishy stuff. Can emotions be data? When Hu and fellow lab student, Travis Rich (also his roommate, is there any other way when you are 20-something?) invented Gif Gif, the theory of Quantify took shape. I sat down with Kevin to learn how he plans to change the way we live and digest information.

What happened with Pantheon after the NY Times Magazine cover?
When the cover hit, we got a lot of attention. We had a couple hundred thousand page views. Amy Yu led the project and I joined. We ran into a lot of controversy because people, and The New York Times, focused on the rankings rather than our goal of cultural production over time. We were less interested if a celebrity were number five or six but rather the aggregate: How many physicists have changed over time, what is our country’s cultural composition? Instead we had angry e-mails from Canadians asking why Avril Lavigne was above Frank Gehry.

The real point of the project was to see cultural production and how it changes over time. We think of cultural production, in the broadest sense, as information that’s transmitted by nongenetic means, like what we’re doing right now. Anything that’s not encoded in our DNA: The shoes we wear, the coffee we drink, and the language we speak. We consider that all to be culture and we proxy it by people.

What’s on your desk today?
DIVE. It’s trying to make data visualization accessible. It’s trying to democratize the use of data visualization, like the charts you see in The New York Times. One of the real powers of Pantheon was that anyone could look at this tree map or scatter plot or diagram and understand the story being told. The trouble is it takes a long time to build this tool. The New York Times has great interactive visualizations but they have a whole team dedicated to it.

DIVE is a way that people can automatically build visualizations, allowing a journalist to easily imbed a data-driven graphic, or an educator or researcher to easily build a visual tool.

How would you define the challenge of data visualization?
The fundamental problem is that we’re trying to translate between three worlds: 

  • The world of information: Bits
  • The world of knowledge: Neurons and cells; and 
  • the world of visualization: Pixels
Until we all are cyborgs and can plug in this data and automatically get what we need, we will need pixels. Data visualization is entirely concerned with how we represent these bits in terms of pixels on a 2-D screen. How do we turn the invisible to the visible?

What drew you to explore macro-connections?
I was studying physics but I was kind of frustrated with the current research scope of physics. It seems to me that people are concerned with either what’s very big (cosmology and astrophysics), or very small (high energy physics). But I was interested in learning how to understand everyday phenomena.

I was interested in looking at people who are applying physics to social problems and to things that we do not understand such as organizational structures, social dynamics, and the spread of epidemics.

What do you see that we don’t? How do you apply physics to social structures and problems?
I think it’s mostly a cultural thing. For the longest time social sciences could only tell us how we can think about a problem, not how we can actually solve it. But now we actually have the data to solve the problem. That’s very frightening but it’s very powerful and it’s a very new phenomenon.

Ten years ago, we didn’t have the data to create things like Pantheon. Now we have Facebook and OK Cupid that have great data logs. For the first time, we have actual data about self-identity. We now have how we view ourselves and how we view others. Physics is all about modeling these phenomena.

So these ‘squishy’ social things start to seem more linear?
Yes, exactly. Exactly.

How will DIVE change our lives? And can you already see it taking place?
I can. Imagine if journalists could use data visualization in their articles. Imagine if consultants could use it. The pipe dream is that in the future we have a completely data-literate society where when we talk about policies or about disaster relief, we have real-time, high-resolution, clean data sets and anybody has the ability to think about social issues rigorously.

For many issues, we see them through another person’s interpretation. A great deal of science reporting, for instance, is very second and third hand. Very few people actually read the research paper. Data visualization allows everyone to understand issues. DIVE is trying to close that gap such that when we acquire information about the world, we can get it first hand and we can mine it ourselves.

You sent me a test called Place Pulse before this interview. Why? 
Travis and I had this vision that we want to give computers the capability to reason about objects the way that we do. When computers think of gifs, they think of bits. When we think of gifs or videos, we think of their content. We may think of this video as being very emotionally compelling or this picture being very angry. That’s how we may think of an image but that’s not how a computer does.

Are you’re trying to give the computer emotions?
Yes, to give it the capability to think of media emotionally. It can reason very well, better than humans for anything that’s very computational and linear. But when we try to attach emotional intelligence to computers, we are not yet there. A computer cannot yet measure that this atrium is very clean, but a human can. We need a human in the loop.

We’ve built this comparison tool off the Quantify platform. You can imagine a whole list of comparable media that we can better measure if only we had the tools. How useful would it be if you could search Netflix this way? Or compare articles of clothing and know which one looks better on you or which one is more acceptable? Or compare experiences and know which one is more painful? Quantify allows this.

How do you convince people to give you that data?
We made it fun. Travis and I also built Gif Gif last March and it inspired Quantify. We have two million votes already. People like viewing gifs and contributing to knowledge but furthermore, we can give you a sense of what you like. What is your emotional profile? How did you vote in comparison to others? That makes it more interesting to share.

Who uses Gif Gif now?
People from all over the world use it. I’d say that the demographics are probably mostly teenagers because, really, who’s voting on gifs at 2 p.m. on Tuesday?

There is also a display in the lab called Mirror Mirror linked to Gif Gif. It’s a mirror with a webcam that uses facial recognition to measure emotions and it gives you back a gif. People love it and we didn’t expect people to love it, but it turns out that five-year-old children touring the lab and 60-year-old executives are all in front of it trying to say hi or trying to be angry.

What public opinion would you like to change?
I’d like to change the public’s opinion about experimentation. Human experimentation is an incredibly loaded term, for many very good reasons, and when Facebook said that they were experimenting with people’s newsfeeds, there was outrage. I think it’s kind of absurd. This is how software companies make tools. They test on their users and provide a service for free, and in exchange they use your data set. Clearly, if they give it to the wrong people, there’s potential for evil and abuse. I would like to see people be open and accepting of the fact that by contributing a little bit of anonymous information, they can help scientists better understand bigger issues like information flow, social network formation. I think that that should definitely change.

Why is the Media Lab so illustrious?
What I really look forward to every morning is the conversations I have with the people here in the lab. Gif Gif and Pantheon and DIVE – all those ideas really merged organically and there’s no real source: they all kind of came from the network and from conversations. A lot of people imagine people at the lab as people off in the air dreaming about what the next big thing will be, but really it’s just regular people having conversations and they happen to be asking, ‘what could be impactful?’ We’re aiming towards more paradigm shifts than incremental research. Is this going to be a game changer? Most of the time, the answer is ‘no,’ by definition, but it’s nice to be in a place where that is one of the first questions.

How do you keep going when things get tough on a project?
I’m taking this class at the lab called Tools For Wellbeing, as there’s a big initiative here about wellbeing, especially since MIT isn’t doing so well in that category. Pattie Maes actually teaches it sometimes. Last week’s subject was reframing. How do I reframe the situation? My answer to your question would definitely be to reframe it. Let’s say I’m trying to make this product but a feature isn’t working out. Well, one, can we design around that? Two, can we make do without it?

You dropped out of high school to go to Simon’s Rock School. How was that for you?
Simon’s Rock was probably the most formative two years of my life. It’s 300 kids in the Berkshires in the middle of nowhere in a pretty high-stress academic environment. It was very formative for me and I would do it again, but I don’t know if I’d enjoy it that much.

It’s considered an ‘early college.’ When I transferred to MIT from there, they accepted most of my Simon’s Rock credits.

Where do you get your news?
My media diet is 

  • one third Twitter and Facebook, 
  • one third very specific news sites that I like such as The New Yorker, New York Times, Huffington Post – the classic ones – The Economist – that sort of stuff – and 
  • then one third Reddit.
What event are you looking forward to?
I’m looking forward to the MIT Media Lab’s Spring Members’ Meeting, which is sometime in April. During this meeting, lab sponsors (companies) come by for three days for research demos and updates. I’d love to get member’s feedback on DIVE, FOLD, and QUANTIFY when they’re further along, since outsiders are always candid with their comments and needs.

Secret source?
It’s a lame answer but McDonald’s. I’m a huge McDonald’s fan.

What do you order?
Fries and McFlurry. I grew up with McDonald’s and Lunchables. I try to eat healthier now but that’s definitely my go to. I go there at least twice a week.

That stuff’s poison!
It’s true but it’s too good.

Heidi Legg interviews visionaries and thinkers around us at TheEditorial.com Follow Heidi on Twitter - Facebook


















ORIGINAL: Beta Boston


By Heidi Legg

jueves, 21 de agosto de 2014

Joi Ito: Want to innovate? Become a "now-ist"

Remember before the internet?” asks Joi Ito. “Remember when people used to try to predict the future?” In this engaging talk, the head of the MIT Media Lab skips the future predictions and instead shares a new approach to creating in the moment: building quickly and improving constantly, without waiting for permission or for proof that you have the right idea. This kind of bottom-up innovation is seen in the most fascinating, futuristic projects emerging today, and it starts, he says, with being open and alert to what’s going on around you right now. Don’t be a futurist, he suggests: be a now-ist.

viernes, 12 de julio de 2013

Silk Pavillion – CNC Deposited Silk & Silkworm Construction at the MIT Media Lab


Project Video  (HQ)



Silk Pavillion
2013 CNC Deposited Silk & Silkworm Construction
MIT Media Lab

Prof. Neri Oxman, Markus Kayser, Jared Laucks, Carlos David Gonzalez Uribe, Jorge Duro-Royo

The Silk Pavilion explores the relationship between digital and biological fabrication on product and architectural scales.The primary structure was created of 26 polygonal panels made of silk threads laid down by a CNC (Computer-Numerically Controlled) machine. Inspired by the silkworm’s ability to generate a 3D cocoon out of a single multi-property silk thread (1km in length), the overall geometry of the pavilion was created using an algorithm that assigns a single continuous thread across patches providing various degrees of density. Overall density variation was informed by the silkworm itself deployed as a biological printer in the creation of a secondary structure. A swarm of 6,500 silkworms was positioned at the bottom rim of the scaffold spinning flat non-woven silk patches as they locally reinforced the gaps across CNC-deposited silk fibers. Following their pupation stage the silkworms were removed. Resulting moths can produce 1.5 million eggs with the potential of constructing up to 250 additional pavilions. Affected by spatial and environmental conditions including geometrical density as well as variation in natural light and heat, the silkworms were found to migrate to darker and denser areas. Desired light effects informed variations in material organization across the surface area of the structure. A season-specific sun path diagram mapping solar trajectories in space dictated the location, size and density of apertures within the structure in order to lock-in rays of natural light entering the pavilion from South and East elevations. The central oculus is located against the East elevation and may be used as a sun-clock. Parallel basic research explored the use of silkworms as entities that can “compute” material organization based on external performance criteria. Specifically, we explored the formation of non-woven fiber structures generated by the silkworms as a computational schema for determining shape and material optimization of fiber-based surface structures. Research and Design by the Mediated Matter Research Group at the MIT Media Lab in collaboration with Prof. Fiorenzo Omenetto (TUFTS University) and Dr. James Weaver (WYSS Institute, Harvard University).

Selected Press: Creative Applications, DEZEEN, WIRED, FASTCOMPANY, ARCHDAILY, Treehugger, io9, jaxtapoz, CORE77, GIZMODO, Creator's Project, inhabitat, Forbes and more.

jueves, 7 de febrero de 2013

MIT Builds An Open-Source Platform For Your Body

ORIGINAL: FastCo
FEBRUARY 5, 2013


About This Series

Meet the people and discover the personalities driving the world's most radical, disruptive, and creative companies.READ MORE
MIT Media Lab's 11-day health care hackathon pulled students and big companies together with a common goal: Healing a broken industry.

Hack Thyself. The goal of the annual MIT Health and Wellness Hackathon is to jump-start an open source platform where apps that track all different aspects of your bodily health can exchange information. Here are this year's projects from the MIT Media Lab's 11-day event.
Siberian temperatures. Eleven grueling days, navigating rough terrain. Six teams, matched for talent, competing for glory at the end. The Iditarod? Nah, just the annual MIT Health and Wellness Hackathon.

This isn’t your average social app-fest. The goal is to jump-start an open source platform where apps that track all different aspects of your bodily health can exchange information. It’s a Sisyphean task, since most digital health solutions today are trapped in silos, but the organizers believe they can change that by enfranchising big companies instead of trying to disrupt them.

Healing The Health Industry
The tradition in health care technology is, ‘This is our device, we make our own software,’” says Dr. John Moore, who organized the hackathon. “The goal is to connect that bit of knowledge to the rest of your health experience. Just keeping track of your step count, for example, won’t let you change the rest of your life.”"JUST KEEPING TRACK OF YOUR STEP COUNT, FOR EXAMPLE, WON’T LET YOU CHANGE THE REST OF YOUR LIFE.

To unify the segmented market for health technology takes heavy lifting on the engineering side, since much of the progress made by private companies hasn’t been shared back to the community. Here, each team is required to use open source and open standard tools so that things work together seamlessly: specifically, the Lab's patient-centered CollaboRhythm platform and the Indivo X system for personalized health records.

Working from a common platform takes an extra effort to build,” Moore says, “but it ensures that the prototype will be something that has legs.” With Boomers aging and a lack of innovation coming from industry, the upside for these projects could be huge--but undertaking them is intimidating. “We thought we’d have to reject people,” says Moore, “but instead we just scared them off.

Hacking Together Industry Partnerships
The teams encamped on the Media Lab’s sixth floor, overlooking a Charles River initially frozen so solid you could stroll over to the Back Bay for pizza. This is the fourth such hackathon sponsored by the Lab’s New Media Medicine research group; when it started, the competition was 20 mostly MIT students who spent their winter break experimenting with open source innovation platforms for health care. Now the group includes an international assembly of professors, doctors, graduate and undergraduate students, as well as engineers from MIT sponsor companies like MIT sponsor companies like ViiV, Humana, Motorola and Fleury. Still, it’s only a start.

The hackathon itself is not enough to produce change, but it's an opportunity to expose important players in the ecosystem--pharma, insurers, medical diagnostics companies, startup entrepreneurs, consumer electronics companies--to the value of using and contributing to these platforms,” says Moore. “It’s rare to get these players to converge, but these 80 people are influencers, and now they know each other so they can collaborate. Big innovations will come when they all see how they can benefit each other.”

Matched into six project teams before arriving in Cambridge, the groups come at problems from different interests and areas of expertise, then work to create solutions that are more than just one-off apps or devices.

It would take years for all of these sectors to realize the potential that they have seen unfolding in the two weeks of this event,” says Moore. “It is this seed that may lead them to build their products differently and encourage that to collaborate with partners from other sectors using the same tools.

How Do You Incentivize Product-Ready Hacks?
The focus here is on producing commercially viable products. “Suddenly, you [can] have a really well-rounded tool that can be at the level of sophistication where you can get funding for a startup or a research grant,” says Moore. "We make sure the business people are supportive, and not just looking at today's business models.... We squash negativity. That's a big problem in the health space, where innovative ideas are often killed with comments like, 'Nah, nobody will ever get paid for that.' I act as the benevolent dictator to enforce that.""WE SQUASH NEGATIVITY. THAT'S A BIG PROBLEM IN THE HEALTH SPACE."

At the Health and Wellness hackathon, the winners aren't rewarded with cash since winning is only the beginning. Kaiser Permanente donated $15,000 to support the teams during development, instead of forcing them to go out-of-pocket to build their hacks. Awarding money to participants helps unshackle some of the crazier ideas; because current medical systems are plagued with legacy software, Moore wants participants to think blue-sky without being too constrained by cost. “We’re looking for optimal solutions,” Moore says, “more 'greenfield' kind of ideas." (Read on for examples from this year's projects.)

The Lab also provides on-site mentors in the form of software developers, professional UI designers, and video teams to bring projects to fruition. A team member with business experience is attached to each group, but is forbidden from dismissing good ideas that may be promising, but don't have a traditional revenue stream.

By the end of the marathon event, the Charles had thawed, and signs of encouragement were everywhere inside as well, says Frank Moss, a health care entrepreneur and former MIT Media Lab director. Driven by demands from patients and clinicians, he says everyone from the White House to the business community is “saying things we were saying four years ago,” around the time of the inaugural Health and Wellness hackathon. Here’s wishing the industry a speedy recovery.

The Projects
Last year’s Health and Wellness Hackathon winners, dubbed the Chameleon team, went on to launch a company called GeckoCap which produces a device for tracking asthma inhaler usage. The company, which was named “One of the Best Gadgets of CES 2013,” is currently raising funds on Indiegogo

Here are some of this year’s entrants.

hiVIVA

Adherence to medications is the key to keeping HIV/AIDS patients healthy, but compliance can be a problem. This app uses gaming to encourage users to take their pills. Users begin by uploading a photo they love to the home screen on their cellphone. Each morning, that image starts out fuzzy; the goal of the game is to sharpen it over the course of the day, based on adherence to the patient’s medication schedule. The system also gives patients a “virtual pill box” containing images of the actual pills in their regimen, to avoid confusion. Data is simultaneously sent to the patient’s physician via Bluetooth, and an accompanying device will eventually allow a patient to easily test his own blood. A prototype is currently being tested in Bangladesh.

Beacon
The Congestive Heart Failure team built a monitoring device called Beacon that would allow elderly patients with chronic conditions to stay in their homes longer. The device sits in a bedroom and is linked wirelessly to sensors throughout the house. If the sensor determines that the patient is moving less than normal, a light on the top of the main unit will turn yellow--alerting the patient to take her blood pressure, or step on a scale. Sudden weight gain, for example, is a sign that the patient’s condition is worsening. Data will be transmitted to the patient’s doctor, who can then communicate with the patient to see if a change in medications is called for, or if more serious intervention is required.

My Op
This app is designed to help patients who are about to undergo surgery for endometriosis learn about what to expect beforehand without scaring themselves by searching Google for information. Post-operatively, the app helps doctors assess how their recovery is going. The biggest problem, developers say, is that patients with this condition are so accustomed to being in pain that they often don’t recognize the severity of their symptoms after surgery, and thus fail to report them to their physicians until they’ve become acute. The My Op app allows doctors to monitor self-reported symptoms, and either text or have a video chat with patients if symptoms are concerning before they worsen.

The Brady Glove (left), The Tremo Cup (right)
AEON Health’s Parkinson’s disease devices
This group built a web-based platform to assess and manage Parkinson’s symptoms at home, allowing a patient to better control his own condition.

The Tremo Cup, which the patient uses to take medications several times a day, detects tremors, which correlate to how well a medication is controlling symptoms. By monitoring data, doctors can assess how long a medication is working, and if the timing or dose needs to be adjusted. It also allows a patient to see if he can influence the efficacy of the medication by adjusting exercise, food, or sleep.

The Brady Glove has sensors in each finger that allow a doctor to detect Bradykinesia–-the slowness of movement that is a prime indicator of Parkinson’s disease. Neurologists can assess the severity of a patient’s symptoms by asking him to tap his fingers, open and close his fist, and alter the position of his palm--the classic tests for Parkinson’s--then adjust his meds to help control symptoms.

Pressure Free
This team’s goal was to find a way for a patient to track and lower her blood pressure with minimal involvement by a physician. The solution was an app with three integrated devices: 

  • a blood pressure cuff that sends data to a dashboard; 
  • a Fitbit to measure how much the patient moves; and 
  • a container that monitors how many pills are still in the bottle
Forget to take your meds, and the 3-G powered pill bottle will send you a text message reminder without having to sync your device. In addition, the app will allow patients to invite friends to act as motivators, sending messages and videos to encourage compliance. The pill bottle, designed by a company called Adhere Tech, is already in development. 

Epicenter
The Epicenter team tackled the problem of controlling epileptic seizures through diet and biofeedback. The Ketogenic Diet app allows patients to track what they eat, measure the ketones they produce, and report side effects to doctors. A Ketogenic diet--high in fat and proteins, low in carbs--has been shown to be effective in controlling seizures, but is tough to follow. This app builds in recipes and meal suggestions, and encourages compliance by giving the patient a visual record of her progress.
Epilepsy app (left), epilepsy cap and wrist senor (right)

Epicenter also created a seizure tracking tool, where the patient can record seizure triggers, log how long the seizure lasted, and document feelings afterward. The patient’s doctor can analyze the data and intervene where necessary, and a gaming device using a neurofeedback cap that measures brain currents and a wrist sensor that measures galvanic skin response allows patients to influence their condition via biofeedback.

sábado, 17 de noviembre de 2012

Open university: Joi Ito plans a radical reinvention of MIT's Media Lab

ORIGINAL: Wired
15 November 12

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This article was taken from the November 2012 issue of Wired magazine. Be the first to read Wired's articles in print before they're posted online, and get your hands on loads of additional content by subscribing online.

Joi Ito, 46-year-old director of MIT's Media Lab since last September, has just selected the faculty's newest outpost: the troubled streets of downtown Detroit. "I was in a rough neighbourhood there yesterday, where there are miles and miles of bombed out buildings, and it just blows your mind to see a bunch of kids building urban farms," he says back in his office in Cambridge, Massachusetts. "They have no streetlights. If you connect a streetlight to the grid, it gets controlled by the city and regulated. So they're thinking, how can we create solar-powered low-cost streetlights, as that will lower crime? They have a maker space in a church, a place where the kids can learn how to build a computer, a bike shop where they can learn how to do repairs. The kid who runs this place, Jeff Sturges, is awesome.We're sending a bunch of Media Lab people to Detroit to work with local innovators already doing stuff on the ground."

Welcome to Ito's vision for opening up the 27-year-old Media Lab, one in which -- for example -- urban agriculture might be researched in Detroit; the arts in Chicago; coding in London; and in which any bright talent anywhere, academically qualified or not, can be part of the world's leading "antidisciplinary" research lab. "Opening up the lab is more about expanding our reach and creating our network," explains Ito, appointed director in April 2011. His prior career spans venture capital and angel investing, Creative Commons and the Mozilla Foundation, nightclub DJing and cofounding the first Japanese internet service provider -- but he never actually earned an academic degree. Although, as Ito sees it, the formal channels of academia today inhibit progress. "In the old days, being relevant was writing academic papers. Today, if people can't find you on the internet, if they're not talking about you in Rwanda, you're irrelevant. That's the worst thing in the world for any researcher. The people inventing things might be in Kenya, and they go to the internet and search. Funders do the same thing. The old, traditional academic channel is not a good channel for attracting attention, funding, people, or preventing other people from competing with you.

"Being open, you're much less likely to have someone competitive emerge and you're also much more likely to find somebody who wants to come to work with you. Innovation is happening everywhere -- not just in the Ivy League schools. And that's why we're working with you guys [at Wired] too -- in the old days, academics didn't want to be in popular magazines. Openness is a survival trait."

By opening up the Media Lab, Ito hopes to move closer towards his goal of "a world with seven billion teachers", where smart crowds, adopting a resilient approach and a rebellious spirit, solve some of the world's great problems. His is a world of networks and ecosystems, in which unconstrained creativity can tackle everything from infant mortality to climate change. "We want to take the DNA [of the lab], the secret sauce, and drop it into communities, into companies, into governments," he says. "It's my mission, our mission, to spread that DNA. You can't actually tell people to think for themselves, or be creative. You have to work with them and have them learn it themselves."

The lab, opened in 1985 by Nicholas Negroponte and former MIT president Jerome Wiesner as part of MIT's School of Architecture and Planning, was intended from the start to foster antidisciplinary thinking. It was, according to a 1984 briefing document by Negroponte, "designed to be a place where people of dramatically different backgrounds can simultaneously use and invent new media, and where the computer itself is seen as a medium -- part of a communications network of people and machines -- not just an object in front of which one sits." The same document -- written the year the Apple Mac was born -- stated: "Today, computers are awkward, if not debilitating, to use. The average so-called personal computer arrives with unreadable documentation, the bulk and weight of which usually surpass that of the machine itself." So how does the lab remain relevant in an era of sentient, voice-recognising and multi-sensor-embedded smartphones?

To Ito, that role is not about creating spun-out products -- although celebrated products spawned by the lab include Guitar Hero, the Kindle, the XO laptop, LEGO Mindstorms, and the foldable CityCar. As Ito sees it, the lab's mission "is to come up with ideas that would never be able to occur anywhere else because most places are incremental, directed and disciplinary". And that means turning the lab into a platform rather than a physical place. "Nicholas comes from a slightly top-down, design-led background. I come from a very unorthodox community-building place --Creative Commons, Mozilla, Witness, Global Voices -- which are all about creating movements. To me there's a science to community building. If you extend the Media Lab as a network, and bring in different types of partners and nonprofits, and create more diversity, the lab itself could become a mission, a movement. People think of the lab as a lot of smart people in a really cool-looking building making really cool gadgets. But I want it to have a much stronger normative political message -- a lot of the kids at the Media Lab today don't want to make more money, don't want to become immortal, they just want to figure out how to fix this unhealthy system we have. There are lots of kids who are not happy with this massive consumerism, this unsustainable growth, but who have really smart science and technology values. That's a type of person we can draw into what I think will become a movement."

And that will come from pursuing distinctly unconventional research goals. "We aim to capture serendipity. You don't get lucky if you plan everything -- and you don't get serendipity unless you have peripheral vision and creativity. [Conventional] peer review and scholarship play by predetermined rules -- that five other people agree that what you're doing is interesting. Here, even if you're the only person in the world who thinks something's interesting, you can do it. Our funding model allows our students to do anything they want without asking permission. It's like venture capital: we don't expect every experiment to succeed -- in fact, a lot are failures. But that's great -- failure is another word for discovery. We're very much against incrementalism -- we look for unexplored spaces, and our key metrics for defining a good project are uniqueness, impact and magic."

During a two-day "Sponsor Meeting" at the lab in late April -- open to a few hundred Media Lab friends and financial backers, ranging from BT to Bank of America, Hasbro to Hallmark Cards -- Ito set out some of his key principles. These included: "Encourage rebellion instead of compliance"; "Practice instead of theory"; " Constant learning instead of education"; "Compass over map". "The key principles include disobedience -- no one ever won a Nobel prize by doing as they're told," he explains later. "And it's about resilience versus strength -- you don't try to resist failure, you allow failure and bounce back. And compass over map is important -- you need to know where you're going, but the cost of planning often exceeds the cost of actually trying. The maps you have are often wrong. These principles affect and apply to just about any organisation."

Because all the rules have been torn up. "Today any kind of science that's used to predict the future becomes useless. The world is no longer incremental or linear. A lot of risks come from the periphery, not what you're focused on. In the old days, you needed hundreds of millions of dollars and armies of people to do anything that mattered. Today a couple of kids using open-source software, a generic PC and the internet can create a Google, a Yahoo! and a Facebook in their dorm room, and plug it in and it's working even before they've raised money. That takes all the innovation from the centre and pushes it to the edges -- into the little labs inside the Media Lab; inside dorm rooms; even inside terrorist cells. Suddenly the world is out of control -- the people innovating, disrupting, creating these tools, they're not scholars. They don't care about disciplines. They're antidisciplinary."

Ito himself is a product of the periphery. Born in Kyoto, he moved as a child to Canada and then Michigan. Although he attended Tufts and the University of Chicago, he dropped out before completing a degree, frustrated at the limitations of conventional teaching. Yet, partly through his research-scientist father, he had access to academics while growing up: "When I was in high school most of my learning came from college professors -- I'd just email professors in Berkeley and MIT. I figured out a way to cobble together an education using academic institutions without actually getting a degree. So I'm an antidisciplinary self-made academic. Because I've come from the outside, I'm more focused on learning than education."

"My problem is I'm interested in everything -- I have a lack of focus," says Ito. "But my bug turns into a feature at the lab. Because the Media Lab is interested in everything. My main skill is connecting and trading contacts. When you have 350 random projects and 26 groups and 75 members [at the lab], the director needs to create context, make connections, pull the pieces together. My favourite thing is managing communities and creating energy. That's really what the Media Lab is -- it reminds me of an open-source community like Mozilla." He knows he will have succeeded when "the Media Lab name is as ubiquitous as the word internet".

He has convened an advisory council made up of friends and contacts, including TED's June Cohen ("It's no accident that June is one of our advisers. There's a lot we can learn from TED, the way the branding works and the platforms"); Grey-lock's Reid Hoffman; writer Seth Godin; Alberto Ibargüen of the Knight Foundation; Michelle Kydd Lee of the CAA Foundation; and -- his mentor on "wisdom" -- Peter Gabriel. So who sets the lab's broad priorities? "I'm working with the faculty to come up with the things they're interested in," Ito says. "The seven billion teachers, or Tod Machover wanting to make the eighth art -- these initiatives we're building on internally. But we'll also need the funding. Probably a third of my energy goes towards fundraising. So the priorities will be set by what are three to six big stories. One of the problems we have right now is there are 26 groups and 350 projects. The ones that become priorities will be those that can attract the funding, but also have the uniqueness, impact and magic. There's also pattern recognition: when you go mushroom hunting, you can't focus or you won't spot the mushrooms. It's when you stop looking that the mushroom patterns pop out. A lot of the priority setting isn't about laser focus. It's that combination of execution and peripheral vision. Part of our job is about picking priorities that others don't do -- if you can do what you do anywhere else, you shouldn't be at the Media Lab. You have to be a true misfit."

Ito, who married Mizuka Kurogane four years ago in Japan, has pledged to travel less -- two years ago, a Wired Infoporn (10.10) showed that between 1 January 2009 and 5 April 2010, he was away from home for 372 out of 460 days. "This year I barely left Boston for six months," he says. "I'll probably start travelling more again, but not as intensely as it used to me. Before, my job was running around mostly making connections. Now at the Media Lab I pick the colour of the furniture and make hires -- lots of face to face stuff." He's also on various boards, including those of TheNew York Times, the Knight Foundation and the MacArthur Foundation.
What about resistance to change as he imposes his ideas? "Surprisingly, knock on wood [he laughs], people are excited about the direction we're going. I listen a lot, I'm not pushing the lab in a direction it doesn't want to go. My background is community development. And MIT as an institution is trying to constantly reinvent itself. So far so good. We'll see if it's a honeymoon period or long-term relationship."

Ito was originally rejected for the role because he lacked academic credentials. "The search committee said out of courtesy that I should send him an email appreciating his interest but that he didn't qualify," Nicholas Negroponte recalls over breakfast at the Charles Hotel in Cambridge. "Six months later, we came up empty, with no candidate. And Joi's name floated back to the top of the list. I sent Joi an email -- where are you? He said, I'm in the Bahamas. I said get your ass up to MIT as soon as you can. He came two days later."

Negroponte, director from 1985 to 2000, had been no fan of Ito's predecessor, Frank Moss, who took over in 2006 from Walter Bender. "They brought in the wrong person," Negroponte says bluntly. "The lab went through a five-year period like the dark ages." So when Ito was appointed, Negroponte wanted the press release headlined: "University dropout named director of Media Lab". "But," he says with raised eyebrows, "the fact that he didn't have a degree was buried near the last paragraph. That's the good Peter Thiel -- if you do drop out and do something creative, more power to you."

What does Negroponte -- the original investor in and a columnist for Wired 20 years ago -- see as the lab's role today? "It has at least three roles," he says. "To do what normal market forces do not do; market forces are great for what's not important in your life. In an organisation like Media Lab, you can take a level of risk that's unparalleled. You can start 40 projects of which only two succeed. VCs can't do that; corporate research can't do that -- because you have this other product line called people. The most interesting ones who come out of the lab have worked on projects that failed. And the third role is its antidisciplinary nature. It's been the only part of MIT that's a lab and an academic department -- we're really church and state. It worked."

What importance does he accord to commercial spinoffs? "Very small." Take littleBits, founded by Media Lab alumna Ayah Bdeir, which produces modular electronics kits and in which Negroponte is an investor. "Whether littleBits succeeds or not is inconsequential. I hope she succeeds, as an investment. But startups are perforce small -- you've got to focus, the blinders get narrower. By definition it's not big thinking. I don't measure success by a list of 50 things that were born at the Media Lab -- e-ink; that's not important. The important part is that people were looking at electronic paper, at display techniques -- and whether that particular one worked, it brought us reflective displays in general, and the e-book. It had bigger effects."

Why does he think that efforts to create overseas spinoffs of the lab proved unsuccessful? "There was an attempt to take it to Japan, Germany, Sweden, France, Spain, Ireland, India -- you think we'd learn our lesson. None of them took. In the US, there are half a dozen [institutions] that call themselves media labs. And none of them is like it at all. The idea clearly isn't 'generalisable'. It's the uniqueness of MIT -- it's both porous like Swiss cheese, and has an absence of other departments. So nobody when we founded it said, 'Wait a minute, I do that.' When we decided to call it the Media Lab, I remember a meeting in 1983 -- 'You mean media, as in TV, newspapers?' When I said yes, the answer was: 'It's all yours. Good luck.'"

What big problems does Negroponte -- founder of the One Laptop Per Child project -- believe the lab can help solve today? "The biggest is eliminating poverty. How do you have a world of infinite zero-cost energy, infinite zero-cost education, how do you make a creative society -- all these seemingly unrealistic things? Whatever path you take, you know the answer is through technology. In a world where technology is increasingly a bad word, it is up to an organisation like the Media Lab to keep pushing that technological envelope. In our original [1984] paper, it says the Media Lab will be the place where the invention and creative use of new media happen together. Video and TV were invented by engineers, thrown over the fence and used. Photography by contrast was invented by photographers. The entire evolution of photography was led by the people who creatively used it. My argument back in 1980 was that computer science would be like photography. Which at the time was near heresy."

So if he were starting from scratch today, what would be different? First, he says, he would abolish academic tenure. "A terrible thing." Research priorities "would be in synthetic biology, not computing. I'd fill the building with Ed Boydens, and would look to where nature and science inform each other. I'd look in places where Neri [Oxman] spends her time. The fact that she, Ed Boyden and Hugh Herr work together is amazing. I'd look to that for inspiration, whether the lab is a platform, a school of thought -- but probably not a huge campus building. The days of institutions may be over -- it would probably not be a building if we started today." Ito disagrees. "The building and the space and the core faculty are really important -- they're the custodians of the DNA," he says.

"The lab will be a network. You'll find the lab and its fellows, its affiliates, all over the world. I've just picked Billionaire Boys Club designer Christopher Bevans as a fellow of the lab; you'll be able to touch the Media Lab a block away from you in London, in all kinds of networks. Instead of just having large companies as our members, we'll have other academic institutions, and governments, and philanthropists, and arts bodies. You'll see more of the Media Lab in every kind of area."

The Media Lab timeline

1985 
Media Lab (cofounded by Nicholas Negroponte and former MIT president Jerome Wiesner) opens in an IM Pei building.

1990
The lab demonstrates the world's first real-time, moving synthetic hologram.

1994
The lab posts the web's first electric postcard where text and image are "mailed" via the net.

1995
Harmonix is founded by lab alumni Alex Rigopulos and Eran Egozy. It developed Guitar Hero, Rock Band and Dance Central.

1996
Patent filed for e-ink, now used in e-readers such as the Kindle. CSound is developed -- it's capable of delivering an entire Beethoven symphony over the internet in about ten seconds and rendering it in real time at CD quality.

1998 
Launch of LEGO Mindstorms, developed in collaboration with the lab. MPEG-4 is released by the International Standards Organisation, featuring Media Lab's Structured Audio sound-processing tech.

2000
Walter Bender succeeds Nicholas Negroponte.

2001
Media Lab Europe opens in Dublin.

2002
Minority Report uses the lab's gesture-recognition tech.

2005
Negroponte announces the "$100 laptop" at the World Economic Summit in Davos, Switzerland.

2006
Frank Moss succeeds Walter Bender as director.

2007
World's first robotic ankle-foot prosthesis prototype is introduced.

2008
Nexi -- a mobile, dextrous, social robot -- makes her debut.

2010
The new Media Lab building, designed by Maki and Associates, opens.

2011
Joi Ito becomes Media Lab director.

2012
Hiriko, the commercial version of the lab's folding, stacking electric car, is introduced in Brussels MV.

David Rowan is the editor of wired. He wrote about Rakuten in 09.12